T cells are positioned at the frontline of the body's immune system to fight infection, cancer, and autoimmune disease. While different subtypes of T cells exist, how these cells take their different ...

Northwestern researchers have shown that when it comes to cancer vaccines, arrangement can be just as important as ingredients. By repositioning a small fragment of an HPV protein on a DNA-based ...

Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer needed. The cellular waste disposal system called the proteasome is best ...

Cigarette smoking is prevalent worldwide and causes numerous diseases, yet our understanding of how cigarette smoke (CS) causes serious respiratory illnesses is incomplete, and has held back the ...

An innovative approach supercharges the innate immune system to provide a first line of defence against respiratory ...

Throughout the past decade, Northwestern University scientists have uncovered a striking principle of vaccine design: Performance depends not only on vaccine components but also on vaccine structure.

A genetics‑guided drug, compound 6, targets CARD9 to subtly calm gut inflammation in Crohn’s disease, pointing to safer, longer‑lasting, precision treatments.

The in situ formed hydrogel vaccine creates an immune niche to coordinate the spatiotemporal dynamics of vaccine components and dendritic cells, eliciting durable and enhanced immunity against ...