Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

The mechanism for muscle stem cells repair could inspire therapeutics for muscle loss caused by injury, aging and weight-loss medications.

Researchers have investigated the role of a certain enzyme in regulating energy in muscle and exercise performance for ...

The first comprehensive cell atlas of aging human muscle reveals the intricate genetic and cellular processes behind muscle deterioration and mechanisms to counteract it. How muscle changes with ...

When bones break and there is extreme tissue loss--such as after a car accident or a battlefield injury--current treatments don't often lead to effective healing. But certain stem cells from skeletal ...

Researchers found muscle stem cells temporarily reduce PFKM-driven glucose metabolism after stress, rerouting fuel to antioxidant repair before rebuilding. Targeting this metabolic checkpoint could ...

Researchers identified a critical AMPK phosphorylation site that regulates mitochondria, muscle contraction, and sugar ...

As we age, our muscles atrophy. Earlier this year, researchers found that hepatocyte growth factor (HGF), a protein critical in skeletal muscle development loses its functionality due to nitration as ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.