The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

A new genome-wide mapping method finally shows how thousands of genes connect to drive disease. Biomedical researchers are working intensively to identify the genes that contribute to disease, with ...

Large-scale human genetics studies have shown that many risk variants for common and complex diseases sit in the non-coding ...

Researchers develop a groundbreaking genomic mapping to reveal how genes interact to cause diseases, paving the way for ...

One of the biggest quests in biology is understanding how every cell in an animal's body carries an identical genome yet ...