Explore the breakthrough of lab-made lncRNA by University of Toronto Engineering for new drug discovery potential.

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new approach to drug discovery that has already yielded some promising ...

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening ...

Compared with human-specific transcriptional factors, human-specific lncRNAs identified upon human lncRNAs’ orthologs in mammals have greatly evolved DNA-binding sites in archaic and modern humans in ...

Sometimes highly impactful serendipitous discoveries are made when performing genetic loss-of-function studies that were initially focused on putative tumor suppressors or other hypotheses.

A research collaboration based in Kumamoto University (Japan) has identified a novel lncRNA, Caren, that is abundantly expressed in cardiomyocytes. They showed that it enhances energy production by ...

A newly revealed role of lncRNAs in the deadly malaria parasite, Plasmodium falciparum, has opened new avenues for targeted therapeutic strategies. Malaria continues to be one of the most critical ...

An Immune-metabolic signature (IMMETCOLS) identifies three clusters in mCRC with different immune-phenotype distribution and potential clinical implications. Deep neural networks and association with ...

Use of chemotherapy and loco-regional therapy for stage IA triple-negative breast cancer and their association with oncologic outcomes: A cancer registry study. This is an ASCO Meeting Abstract from ...

Patients with overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a very rare and severe neurodevelopmental disorder with profound implications for their ...